Schematic illustrating the strategy of the nanoneedle-based delivery of bioprobes into the cell, along with the combined fluorescence and bright-field images showing the nanoneedle penetrating through the cell membrane, and the quantum dots (in red) target-delivered into the cytoplasm and the nucleus of a living cell. (Credit: Image courtesy of University of Illinois at Urbana-Champaign)From Science Daily:
ScienceDaily (May 6, 2009) — Researchers at the University of Illinois have developed a membrane-penetrating nanoneedle for the targeted delivery of one or more molecules into the cytoplasm or the nucleus of living cells. In addition to ferrying tiny amounts of cargo, the nanoneedle can also be used as an electrochemical probe and as an optical biosensor.
"Nanoneedle-based delivery is a powerful new tool for studying biological processes and biophysical properties at the molecular level inside living cells," said
Min-Feng Yu, a professor of mechanical science and engineering and corresponding author of a paper accepted for publication in Nano Letters, and posted on the journal's Web site.
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