One Speck Of Blood Or Tissue May Be Enough To Diagnose Cancer

From Times Online:

A drop of blood or speck of tissue no bigger than a full stop could soon be all that is required to diagnose cancers and assess their response to treatment, research suggests.

New technology that allows cancer proteins to be analysed in tiny samples could spell the end of surgical biopsies, which involve removing lumps of tissue, often under general anaesthetic.

Researchers at Stanford University, California, have developed a machine that separates cancer-associated proteins by means of their electric charge, which varies according to modifications on the protein’s surface.

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Finding Pages From Browser History

From Technology Review:

A new tool aims to make a Web browser's history more useful.

Web browsers remember the sites that they have visited in the past, but few people seem to use this information. Jing Jin, a graduate student at Carnegie Mellon University, has developed a new browser-history tool, which she and her colleagues developed after studying how people use their browser history. They demonstrated the prototype in a presentation this week at the Computer-Human Interaction (CHI 2009) Conference, in Boston.

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Brown Fat: A Fat That Helps You Lose Weight?

From Time Magazine:

For most people, fat is a burden. It doesn't really matter whether it appears as cellulite on our thighs or cholesterol in our veins — we just don't want it.

But it turns out that our bodies also make a unique form of fat tissue that behaves remarkably unlike any other: rather than storing excess energy, this fat actually burns through it.

It's called brown fat (as opposed to the more familiar white fat that hangs over belt buckles and swings from the backs of arms), and a series of papers published in the New England Journal of Medicine confirm for the first time that healthy adults have stores of this adipose tissue, which researchers hope to study further as a potential new weight-loss treatment.

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Google CEO Sees Future For News In Advertising

From The Globe And Mail:

SAN DIEGO — Google's CEO Eric Schmidt recommends that news organizations continue to rely on advertising but seek new ways to reach readers.

Without providing specific recipes, Mr. Schmidt's speech Tuesday lays out a few possibilities.

One is a site for medicine similar to the online encyclopedia Wikipedia, which lets users collectively contribute and edit entries.

He says there's still room for subscription and pay-by-the-piece journalism but he emphasizes advertising, the source of 98 per cent of Google Inc.'s revenue.

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Oldest Stone Blades Uncovered

Cutting-edge technology. A stone core (lower left) and three of the recently found blades. Credit: Cara Roure Johnson and Sally McBrearty/University of Connecticut

Science Now:

CHICAGO, ILLINOIS--Paleoanthropologists working in Africa have discovered stone blades more than a half-million years old. That pushes the date of the earliest known blades back a remarkable 150,000 years and raises a question: What human ancestor made them?

Not long ago, researchers thought that blades were so hard to make that they had to be the handiwork of modern humans, who had evolved the mental wherewithal to systematically strike a cobble in the right way to produce blades and not just crude stone flakes. First, they were thought to be a hallmark of the late Stone Age, which began 40,000 years ago. Later, blades were thought to have emerged in the Middle Stone Age, which began about 200,000 years ago when modern humans arose in Africa and invented a new industry of more sophisticated stone tools. But this view has been challenged in recent years as researchers discovered blades that dated to 380,000 years in the Middle East and to almost 300,000 years ago in Europe, where Neandertals may have made them (ScienceNOW, 1 December 2008).

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Sleep: Spring Cleaning For The Brain?

On the left, the brain of the well-rested blue fly has low levels of a synaptic protein called BRP in this 3D view from a confocal mircoscope. On the right, the brain of the sleep-deprived fly glows orange in areas of BRP concentration. (Bruchpilot or BRP is a protein involved in communication between neurons.)In the tired fly, the protein is present at high concentartions in three major areas of the fly's brain that are associated with learning. Sleep reduces the levels of this protein, an indication that synapses get smaller and/or weaker. This process of "downscaling" may be important so the brain is reset to normal levels of synaptic activity and can begin learning again the next day. (Credit: Courtesy of UW Health Public Affairs)

From Science Daily:

ScienceDaily (Apr. 11, 2009) — If you've ever been sleep-deprived, you know the feeling that your brain is full of wool.

Now, a study published in the April 3 edition of the journal Science has molecular and structural evidence of that woolly feeling — proteins that build up in the brains of sleep-deprived fruit flies and drop to lower levels in the brains of the well-rested. The proteins are located in the synapses, those specialized parts of neurons that allow brain cells to communicate with other neurons.

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Great Golfers' Brains Have More Gray Matter

From Live Science:

As Tiger Woods goes for his fifth green jacket in this weekend's Masters Tournament, mortal golfers wonder what's inside his head that keeps him winning. Well, chances are his brain actually has more gray matter than the average weekend duffer.

Researchers at the University of Zurich have found that expert golfers have a higher volume of the gray-colored, closely packed neuron cell bodies that are known to be involved with muscle control. The good news is that, like Tiger, golfers who start young and commit to years of practice can also grow their brains while their handicaps shrink.

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Space Station May Stay in Orbit 5 More Years

Photo: The International Space Station as seen by the departing space shuttle Discovery. NASA

From FOX News:

The U.S. and major foreign partners on the International Space Station have agreed in principle to keep it operating through 2020, at least five years beyond the current deadline, according to government and industry officials.

There had been looming questions about the future of the space station — which took nearly two decades and more than $100 billion to design and build — because until now, the major partners hadn't committed to keeping it going past 2015.

An extension could give new momentum to the scientific research conducted there, which initially was delayed by false starts and problems finishing assembly of the station.

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Space: The Final Frontier for Cell Phones?

From Time Magazine:

(LAS VEGAS) — The vast, thinly populated expanses of the country that still lack cell phone coverage could be getting an interesting option next year: ordinary-looking cell phones that connect to a satellite when there's no cell tower around.

In June, a rocket is scheduled to lift the largest commercial satellite yet into space. In orbit 22,000 miles above the Earth, the satellite will unfurl an umbrella of gold mesh 60 feet across and aim it at the U.S. That gigantic antenna will let the satellite pick up signals from phones that are not much larger than regular cell phones.

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A Hybrid Nano-Energy Harvester

Photo: Nano hybrid: A dye-sensitized solar cell (top) and a nanogenerator (bottom) sit on the same substrate in the new device. Credit: Xudong Wang

From Technology Review:

The device harnesses both sunlight and mechanical energy.

Nanoscale generators can turn ambient mechanical energy--vibrations, fluid flow, and even biological movement--into a power source. Now researchers have combined a nanogenerator with a solar cell to create an integrated mechanical- and solar-energy-harvesting device. This hybrid generator is the first of its kind and might be used, for instance, to power airplane sensors by capturing sunlight as well as engine vibrations.

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Wind Turbine Imports Increase; Can U.S. Factories Catch Up?

From McClatchy News:

WASHINGTON — Manufacturing of wind turbine parts in the United States grew last year as the market for wind energy boomed, but trade figures show that imports continued at a high rate after years of big growth.

Wind turbine imports from Europe and Asia rose from $60 million in 2004 to $2.5 billion in 2008, according to Customs data reviewed by McClatchy. Imports of other equipment usually, but not always, used for wind power production also increased in the same period. The value of AC generators and towers, for instance, jumped from $84 million to $1.6 billion.

The numbers suggest that there's potential for U.S. manufacturers to seize some opportunities, and some of the largest turbine makers say they're looking for U.S. suppliers.

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Signs Of Earliest Scots Unearthed

From The BBC:

Archaeologists have discovered the earliest evidence of human beings ever found in Scotland.

The flints were unearthed in a ploughed field near Biggar in South Lanarkshire.

They are similar to tools known to have been used in the Netherlands and northern Germany 14,000 years ago, or 12,000 BC.

They were probably used by hunters to kill reindeer, mammoth and giant elk and to cut up prey and prepare their skins.

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'Holy Grail' Drug Can Help Scars Heal, New Research Shows

From The Telegraph:

A drug - called Avotermin - which can help scars heal, has been created for the first time, in a breakthrough described as one of the "holy grails" of scientific research.

Injected into the skin after an injury it encourages the tissue to repair itself more quickly, reducing permanent disfiguration.

Avotermin could be used by surgeons before they operate on patients, to minimize damage, as well as on those who have suffered an injury.

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Study: Biofuel Threatens Water Supplies

From Live Science:

The production of bioethanol may use up to three times as much water as previously thought, a new study finds, becoming the latest work that could burst the biofuel bubble.

A gallon of ethanol may require up to more than 2,100 gallons of water from farm to fuel pump, depending on the regional irrigation practice in growing corn, according to the study detailed in the April 15 issue of journal Environmental Science & Technology.

But the water usage isn't quite so high everywhere: A dozen states in the Corn Belt consume less than 100 gallons of water per gallon of ethanol, making them better suited for ethanol production, the study found.

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Red-Hot Research Could Lead To New Materials

Photo: Two versions of the aerogel -- the RF-only version (left) and the mixed version (right). (Credit: Image courtesy of Missouri University of Science and Technology)

From Science Daily:

ScienceDaily (Apr. 11, 2009) — Recent experiments to create a fast-reacting explosive by concocting it at the nanoscopic level could result in more spectacular firework displays. But more impressive to the Missouri University of Science and Technology professor who led the research, the method used to mix chemicals at that tiny scale could lead to new strong porous materials for high temperature applications, from thermal insulation in jet engines to industrial chemical reactors.

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Printed Supercapacitor Could Feed Power-Hungry Gadgets

From New Scientist:

A supercapacitor – a device that can unleash large amounts of charge very quickly – has been created using printing technology for the first time. The advance will pave the way for "printed" power supplies that could be useful as gadgets become thinner, lighter and even flexible.

Advances in electronics mean portable gadgets are shrinking in size but growing in their energy demands, and conventional batteries are struggling to cope.

Batteries are slow to recharge because they store energy chemically. By contrast, capacitors, which are common in electronics, are short-term stores of electrical energy that charge almost instantaneously but hold little energy.

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Disease In A Warming Climate

Photo: Climate change may lead diseases such as malaria to change their geographical ranges.WHO/TDR/S.Lindsay

From Nature News:

Climate change takes the blame for many dim future prospects: rising sea levels, more frequent droughts and disappearing glaciers, to name just a few. But perhaps the warming trend should be absolved of responsibility for a predicted bump in the global burden of infectious disease.

That's the bottom line of a paper in the April issue of the journal Ecology, which argues that the geographical ranges of infectious diseases are more likely to shift than to expand (K. D. Lafferty Ecology 90, 888–900; 2009). "You often see a list of the 12 terrible things that are going to happen with climate change, and increases in infectious diseases is often on that list," says Kevin Lafferty, an ecologist with the US Geological Survey in Santa Barbara, California. But data from diseases such as yellow fever and malaria, he says, provide "a different reality".

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Research Could Lead To New Non-antibiotic Drugs To Counter Hospital Infections

When worms (Caenorhabditis elegans) ate the bacteria Pseudomonas aeruginosa that were raised on low levels of phosphates, unexpected large red spots appeared in their intestinal tracts. The worms then died, so researchers dubbed the condition "Red Death." They theorized that providing P. aeruginosa with phosphate would protect weakened or immunosuppressed hospital patients from this lethal pathogen. (Credit: John Alverdy, University of Chicago Medical Center)

From Science Daily:

ScienceDaily (Apr. 9, 2009) — Lack of an adequate amount of the mineral phosphate can turn a common bacterium into a killer, according to research to be published in the April 14, 2009, issue of the Proceedings of the National Academies of Science. The findings could lead to new drugs that would disarm the increasingly antibiotic-resistant pathogen rather than attempting to kill it.

Pseudomonas aeruginosa is one of the most serious hospital-acquired pathogens. A common cause of lung infections, it is also found in the intestinal tract of 20 percent of all Americans and 50 percent of hospitalized patients in the United States.

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Losing It: Why Self-Control Is Not Natural

From Live Science:

After dinner last night, I lost my usual self-control and ate half a box of cookies. No wonder. My self-control had been under pressure all day. I righteously refused a muffin at breakfast, didn’t scream at my kid to get out the door although we were late, made a conscious decision not to run over a pedestrian crossing against the light, kept my fist from pounding on the table during a faculty meeting, and resisted the urge to throw an annoying student out of my office.

But by 7 p.m., my self-control mechanism was worn out, and down those cookies went.

The empty box would have been no surprise to Yale University psychologist Joshua Ackerman and colleagues who have discovered that self-control not only wears us down, even thinking about other people's self-control is too much to handle.

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Standing Watch Over A Crowded Space

From The BBC:

On 10 February this year, a defunct Russian communications satellite crashed into an American commercial spacecraft, generating thousands of pieces of orbiting debris.

At the time, some observers put the odds of such an event occurring at millions, maybe billions, to one.

But experts had been warning for years that useable space was becoming crowded, boosting the possibility of a serious collision.

They have argued both for better monitoring of the space environment and for policies aimed at controlling the production of debris.

Over the past two years, a number of incidents have drawn attention to the problem of space debris.

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