Fundamental Mechanism For Cell Organization Discovered

Image: An embryo treated with RNA interference to delay the onset of cell polarization. At the beginning of the process, P granules (green) have already nearly completely dissolved throughout the embryo. However, when the embryo ultimately polarizes, the polarity protein PAR-2 (red) appears on the posterior cortex, and P granules reform by condensation in the vicinity of this posterior region. Credit: Clifford Brangwynne (Credit: Image courtesy of Marine Biological Laboratory)

From Science Digest:

ScienceDaily (May 22, 2009) — Scientists have discovered that cells use a very simple phase transition -- similar to water vapor condensing into dew -- to assemble and localize subcellular structures that are involved in formation of the embryo.

The discovery, which was made during the 2008 Physiology course at the Marine Biological Laboratory (MBL), is reported in the May 21 early online edition of Science by Clifford P. Brangwynne and Anthony A. Hyman of the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany, and their colleagues, including Frank Jülicher of the Max Planck Institute for the Physics of Complex Systems, also in Dresden.

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