Slow Starvation of Brain Triggers Alzheimer's

A 3-D image of brain atrophy differences in mild cognitive impairment (MCI) patients and mild Alzheimer's disease patients. Alzheimer's patients show far more damage overall, especially in cortical areas of the brain. Credit: Dr. Liana G. Apostolova, David Geffen School of Medicine at UCLA

From Live Science:

A slow starvation of the brain over time is one of the major triggers of the biochemistry that causes some forms of Alzheimer's, according to a new study that is helping to crack the mystery of the disease's origins.

An estimated 10 million baby boomers will develop Alzheimer's in their lifetime, according to the Alzheimer's Association. The disease usually begins after age 60, and risk rises with age. The direct and indirect cost of Alzheimer's and other dementias is about $148 billion a year.

Robert Vassar of Northwestern University, the study's lead author, found that when the brain doesn't get enough of the simple sugar called glucose — as might occur when cardiovascular disease restricts blood flow in arteries to the brain — a process is launched that ultimately produces the sticky clumps of protein that appear to be a cause of Alzheimer's.

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Scientists Seek Ways To Ward Off Killer Asteroids

Artist's rendition released by NASA shows an asteroid belt in orbit around a star. Between 500 and 1,000 massive asteroids cross the Earth's path regularly and any one of them could cause a global catastrophe, space experts warned Tuesday, urging quick preventive measures. (AFP/NASA-HO/File)

From Yahoo News/McClatchy:

WASHINGTON — A blue-ribbon panel of scientists is trying to determine the best way to detect and ward off any wandering space rocks that might be on a collision course with Earth.

``We're looking for the killer asteroid,'' James Heasley , of the University of Hawaii's Institute for Astronomy , last week told the committee that the National Academy of Sciences created at Congress' request.

Congress asked the academy to conduct the study after astronomers were unable to eliminate an extremely slight chance that an asteroid called Apophis will slam into Earth with devastating effect in 2036.

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Aubrey de Grey Google Tech Talk On Defeat Of Aging

From Future Pundit:

A friend points out that Aubrey de Grey's October 8, 2007 Google Tech Talk on the defeat of aging has only 402 views. That's a waste of a valuable talk on a very important topic. So here's a post to begin to remedy this waste:

Aubrey and Dave Gobel co-founded the Methuselah Foundation accelerate the defeat of the aging process. Toward this goal Aubrey proposes Strategies for Engineered Negligible Senescence (SENS) to reverse the aging process and repair our bodies to save us from the ravages of aging.

If you are new to SENS and or just haven't heard a recent talk by Aubrey on this topic then watch his lecture.

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Bionic 'Sex Chip' That Stimulates Pleasure Centre In Brain Developed By Scientists

The chip could stimulate the orbitofrontal cortex, which is associated with
the pleasure felt when eating and having sex

From The Daily Mail:

Scientists are developing an electronic 'sex chip' that works by stimulating the pleasure centres in the brain.

The technology, which creates tiny shocks deep in the brain, has already been used in America to treat Parkinson's disease.

Now researchers are focusing on the orbitofrontal cortex, which is associated with feelings of pleasure caused by eating and sex.

A research survey conducted by Morten Kringelbach, a fellow at Oxford University, found the orbitofrontal cortex could be a 'new stimulation target' to help people with anhedonia - an inability to experience pleasure from such activities.

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Bees Acts As Bodyguards For Flowers By Protecting Them From Munching Insects

Photo: A bee hovers above a flower - their buzz scares off other insects such as caterpillars

From The Daily Mail:

Flowers use bright colours and strong scents to attract honeybees to their pollen. But the stripy insects also defend them from other insects, according to a new study in Current Biology.

Their buzzing noise warns off others such as caterpillars who would otherwise munch on the blooms undisturbed.

The researchers, led by Jürgen Tautz from Biozentrum Universität Würzburg, Germany, found many caterpillars possess fine sensory hairs on the front portions of their bodies that enable them to detect air vibrations, such as the sound of an approaching predatory wasp or honeybee.

'These sensory hairs are not fine-tuned,' Mr Tautz said.

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TOP TEN SPACE PHOTOS: Most Viewed Of 2008

From National Geographic:

10. Supernova Creates "Ribbon" in Space

Like a ribbon trailing from a parade float, a streamer of hydrogen gas seems to waft across the stars in an image taken by the Hubble Space Telescope.

Released in July, this festive shot of a supernova remnant was National Geographic News's tenth most viewed space photo of 2008.

Bright stripes within the ribbon—which is actually the shock wave from the stellar explosion—appear where the wave is moving edge-on to Hubble's line of sight.

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Science And The Holidays

From Scientific American:

From greening your Christmas tree to what oil producers could learn from the story of Hanukkah, your guide to the science of the holiday season

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Peripheral Artery Disease: Pain When Walking Can Be Reduced With Moderate Exercise, Study Suggests

From Science Daily:

ScienceDaily (Dec. 25, 2008) — You probably know that poor diet and lack of exercise can lead to dangerous deposits of fatty plaques in arteries. But it is not just the heart that is affected – blood flow can be blocked to the legs too, leading to pain when walking, immobility and even in extreme cases, amputation.

Approximately 20% of us will suffer from this peripheral artery disease (PAD) once we are 65 or over, and with risk factors including smoking, diabetes, obesity and high blood pressure it is on the rise. Surgical intervention can sometimes help, but the prognosis is not good.

Encouragingly, new research by Ronald Terjung et al. published in The Journal of Physiology shows that regular, moderate exercise can go a long way to relieving the symptoms of PAD, and by some unexpected mechanisms.

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Chocolate, Wine And Tea Improve Brain Performance

Chocolate, wine and tea enhance cognitive performance. (Credit: iStockphoto/Silvia Jansen)

From Science Daily:

ScienceDaily (Dec. 24, 2008) — All that chocolate might actually help finish the bumper Christmas crossword over the seasonal period. According to Oxford researchers working with colleagues in Norway, chocolate, wine and tea enhance cognitive performance.

The team from Oxford’s Department of Physiology, Anatomy and Genetics and Norway examined the relation between cognitive performance and the intake of three common foodstuffs that contain flavonoids (chocolate, wine, and tea) in 2,031 older people (aged between 70 and 74).

Participants filled in information about their habitual food intake and underwent a battery of cognitive tests.Those who consumed chocolate, wine, or tea had significantly better mean test scores and lower prevalence of poor cognitive performance than those who did not. The team reported their findings in the Journal of Nutrition.

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Spirituality Spot Found in Brain

From Live Science:

What makes us feel spiritual? It could be the quieting of a small area in our brains, a new study suggests.

The area in question — the right parietal lobe — is responsible for defining "Me," said researcher Brick Johnstone of Missouri University. It generates self-criticism, he said, and guides us through physical and social terrains by constantly updating our self-knowledge: my hand, my cocktail, my witty conversation skills, my new love interest ...

People with less active Me-Definers are more likely to lead spiritual lives, reports the study in the current issue of the journal Zygon.

Most previous research on neuro-spirituality has been based on brain scans of actively practicing adherents (i.e. meditating monks, praying nuns) and has resulted in broad and inconclusive findings. (Is the brain area lighting up in response to verse or spiritual experience?)

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Apollo 8: A Picture Of The Earth From The Moon 40 Years Ago

Apollo 8 "Earth Rise" (Click The Above Image To Enlarge)

Top 10 Scientific Discoveries For 2008

From Time Magazine:

1. Large Hadron Collider

Jean-Pierre Clatot / AFP / Getty

Good news! The Large Hadron Collider (LHC) — the massive particle accelerator straddling the Swiss-French border — didn't destroy the world! The bad news: The contraption didn't really work either. In September, the 17-mile collider was switched on for the first time, putting to rest the febrile webchatter that the machine would create an artificial black hole capable of swallowing the planet or at least a sizeable piece of Europe — a bad day no matter what. No lucid observer ever thought that would really happen, but what they did expect was that the LHC would operate as advertised, recreating conditions not seen since instants after the Big Bang and giving physicists a peek into those long-vanished moments. Things looked good at first, until a helium leak caused the collider to shut down after less than two weeks. Repairs are underway and the particles should begin spinning again sometime in June.

For the other 9, read more ....

The Politicization Of Global Warming

Photo: Dr. William Happer (Source: Princeton University)

Princeton Physicist Calls Global Warming Science "Mistaken" -- Daily Tech

Scientist fired by Al Gore was told, "science will not intrude on public policy".

Noted energy expert and Princeton physicist Dr. Will Happer has sharply criticized global warming alarmism. Happer, author of over 200 scientific papers and a past director of energy research at the Department of Energy, called fears over global warming "mistaken".

"I have spent a long research career studying physics that is closely related to the greenhouse effect", said Happer. "Fears about man-made global warming are unwarranted and are not based on good science."

Dr. Happer views climate change as a predominately natural process. "The earth's climate is changing now, as it always has. There is no evidence that the changes differ in any qualitative way from those of the past."

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Remembering Apollo 8, Man's First Trip To The Moon

Apollo 8 astronauts (l. to r.) William Anders, Jim Lovell and Frank Borman train in the command module one month before their mission. Francis Miller / Time Life Pictures / Getty

From Time Magazine:

Commander Frank Borman was very clear about the fact that no one aboard his spacecraft would be getting drunk on the way back from the moon. NASA had packed a couple of miniatures of brandy aboard Apollo 8 for the occasion — it wasn't enough for three grown men to get anything close to tipsy, but it was a couple of minis more than any crew had ever taken into space before, and when you're piloting a ship that is screaming to Earth at 25,000 miles per hour and you have to hit a narrow atmospheric corridor just 2.5 degrees wide in order to survive the fireball of reentry, a cautious commander would also consider it a couple of minis too many. So Borman ordered his crewmates, Jim Lovell and Bill Anders, to keep the brandy stowed.

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Scientists Doubt Inventor's Global Cooling Idea — But What If It Works?

Ron Ace has filed for a patent on a way to prevent global warming.
George Bridges / MCT

From McClatchy:

WASHINGTON — Ron Ace says that his breakthrough moments have come at unexpected times — while he lay in bed, eased his aging Cadillac across the Chesapeake Bay bridge or steered a tractor around his rustic, five-acre property.

In the seclusion of his Maryland home, Ace has spent three years glued to the Internet, studying the Earth's climate cycles and careening from one epiphany to another — a 69-year-old loner with the moxie to try to solve one of the greatest threats to mankind.

Now, backed by a computer model, the little-known inventor is making public a U.S. patent petition for what he calls the most "practical, nontoxic, affordable, rapidly achievable" and beneficial way to curb global warming and a resulting catastrophic ocean rise.

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SpaceShipTwo’s Carrier Makes First Flight

Virgin Galactic's twin-fuselage White Knight Two carrier airplane takes to the air for the first time on Sunday after weeks of taxi tests. The plane will serve as the mothership for the SpaceShipTwo suborbital rocket plane. Bill Deaver / Mojave Desert News

From MSNBC:

Twin-fuselage White Knight Two goes through test at Mojave airport

A carrier aircraft designed to be the first stage of a commercial spaceline system made its maiden test flight Sunday at the Mojave Air and Space Port in California.

Designed by Scaled Composites, the huge and unique White Knight Two mothership rolled down the runway and muscled itself into the air using four Pratt and Whitney PW308A turbofan engines. The White Knight Two flew for about an hour, departing the runway at roughly 8:17 a.m. PT, safely touching down at the Mojave airport at approximately 9:17 a.m. PT.

"It's a big day," said Stuart Witt, general manager of Mojave Air and Space Port. "I think it's a real reflective time. When everybody's looking for a bailout, there are still people that are doing something for a much larger reason," he told Space.com.

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Facts Melted By 'Global Warming'

Butterflies and polar ice are enlisted in warmist cause Photo: Getty

From The Telegraph:

Something very odd had happened to the daily updated graph on the official Nansen website last weekend, writes Christopher Booker.

Last weekend, that heroically diligent US meteorologist Anthony Watts noticed that something very odd had happened to the daily updated graph on the official Nansen website that shows how much sea-ice there is in the Arctic. Without explanation, as he reported on his Watts Up With That website, half a million square kilometres of ice simply vanished overnight.

This might have brought cheer to all those, such as Al Gore and the BBC, who have been obsessively telling us that the Arctic ice will soon disappear altogether. They were dismayed enough last winter when, after reaching its lowest point in 30 years, the ice bounded back to near "normal". This winter the freeze has been even faster and greater, making the extent of the ice, according to the other main Arctic website, Crysophere Today, 500,000 sq km greater than this time last year. How better to maintain the chosen narrative than to lose that half-million square kilometres simply by "adjusting" the graph downwards?

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Obama Names 4 Top Members Of Science Team

In this Oct. 17, 2007 file photo, John Holdren, professor of Environmental Science and Public Policy in the Department of Earth and Planetary Sciences at Harvard University, speaks at the Carnegie Medal of Philanthropy presentations in Pittsburgh. (AP Photo/Keith Srakocic, File)

From Yahoo News/AP:

WASHINGTON – President-elect Barack Obama's selection Saturday of a Harvard physicist and a marine biologist for science posts is a sign he plans a more aggressive response to global warming than did the Bush administration.

John Holdren and Jane Lubchenco are leading experts on climate change who have advocated forceful government action. Holdren will become Obama's science adviser as director of the White House Office of Science and Technology Policy. Lubchenco will lead the National Oceanic and Atmospheric Administration, which oversees ocean and atmospheric studies and does much of the government's research on global warming.

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Why Does War Breed More Boys?

From PopSci:

Surge of male babies in wartime is due to a male gene, says evolution researcher

A curious shift occurs during and right after a war: more boys tend to be born than girls. It’s been documented for decades in many nations, especially during long conflicts with many troops deployed. The cause of this boy boom has long flummoxed thinkers and scientists. Ideas have veered from the theological—a divine call for new men to replace those lost in battle—to the coital—returning soldiers have lots of sex, and so will be more likely to fertilize at a time in their ladies’ cycle that’s ripe for making boy babies. A new study in the journal Evolutionary Biology rejects them all. Instead, it pins the “returning soldier effect” on a gene expressed by men only. It also shows how researching your family tree can help you place bets on the sex of your next kid.

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Reproduction Of 2,100-Year-Old Calculator Deepens Mystery

From Net Work World:

The model of the Antikythera Device is based on the latest discoveries of the mysterious mechanism

A new working model of the mysterious 2,000-year-old astronomical calculator, dubbed the Antikythera Device, has been unveiled, incorporating the most recent discoveries announced two years ago by an international team of researchers.

The new model was demonstrated by its creator, former museum curator Michael Wright, who had created an earlier model based on decades of study. He demonstrates how the more complete device works in a video originally created on the New Scientist Website. (It's part of an update story by Jo Marchant, author of Decoding the Heavens, an account not only of the device itself but also the century-old scientific quest to recover its meaning.)

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