Stem Cells In Hair Follicles Point To General Model Of Organ Regeneration

Deep roots. For a hair follicle to begin a new phase of growth, an elusive group of cells called the hair germ (bright red) must be activated. This progression of images shows that the hair germ begins proliferating (green) before other cells do, suggesting a two-step mechanism. (Credit: Image courtesy of Rockefeller University)

From Science Daily:

ScienceDaily (Feb. 16, 2009) — Most people consider hair as a purely cosmetic part of their lives. To others, it may help uncover one of nature’s best-kept secrets: the body’s ability to regenerate organs. Now, new research from Rockefeller University gets to the root of the problem, revealing that a structure at the base of each strand of hair, the hair follicle, uses a two-step mechanism to activate its stem cells and order them to divide.

The mechanism provides insights into how repositories of stem cells may be organized in other body tissues for the purpose of supporting organ regeneration.

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Blacksmithing 101: How To Make A Forge And Start Hammering Metal

PM editors Roy Berendsohn (left) and Mike Allen (right) have framed houses and built race cars—but forge steel in the garage? That was something new.

From Popular Mechanics:

PM's home and auto editors took a weekend out to teach themselves how to heat and hammer metal the old-fashioned way. They started by ordering an anvil and making their own blacksmith forge. The sparks flew from there. Click here to download an updated version of the forge plans published in Popular Mechanics in 1941.

If you want to work with metal, there’s one thing you have to confront: You need heat. With it, you can make the toughest metal submit to your will. Without it, you’ll never gain full mastery over this stubborn material.

Over the years, I have been frustrated by my inability to work hot steel. I’ve bolted metal together, welded it and soldered it. But I couldn’t shape it, and so large swaths of the mechanical realm were off-limits to me.

But blacksmithing never felt alien. My father is a metallurgist, descended from generations of 19th-century blacksmiths and born in Germany to shipbuilders whose forges scattered sparks over the shores of the Elbe River and the North Sea. I grew up in rural Connecticut among Yankee mechanics who could forge anything, machine anything, build anything, fix anything—and I’ve been trying to live up to those old-timers’ standards all my life. It wasn’t hard to finally decide to take another step, and teach myself some blacksmithing skills.

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Women Less Tolerant Of Each Other Than Men Are, Study Finds

From Telegraph:

Women are less tolerant of each other than men are, according to a new study which may explain why some women prefer to have a male boss.

The research, published in the US journal Psychological Science, found that women formed a negative view of their peers much quicker than men did.

The team from Emmanuel College in Boston asked male and female college students to rate their room-mates under different scenarios.

When asked to judge how they would rate their room-mates if they carried out a single fictional act of negative behaviour, after they had been otherwise completely trustworthy, women were far more likely to be critical of them.

Men, on the other hand, were much more tolerant.

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Empathy Partly Based On Genes, Mouse Study Shows

New research demonstrates that a highly social strain of mice can learn to associate a sound played in a specific cage with something negative simply by hearing a mouse in that cage respond with squeaks of distress. (Credit: iStockphoto/Brandon Laufenberg)

From Science Daily:

ScienceDaily (Feb. 16, 2009) — The ability to empathize with others is partially determined by genes, according to new research on mice from the University of Wisconsin-Madison and Oregon Health and Science University (OHSU).

In the study, a highly social strain of mice learned to associate a sound played in a specific cage with something negative simply by hearing a mouse in that cage respond with squeaks of distress. A genetically different mouse strain with fewer social tendencies did not learn any connection between the cues and the other mouse's distress, showing that the ability to identify and act on another's emotions may have a genetic basis.

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Infectious Superbug Invades Beaches

From Live Science:

CHICAGO — Add the MRSA "superbug" to the list of concerns you bring to the beach nowadays, a research doctor said today.

It's still safe to go in the water, especially if you shower thoroughly before and after swimming, but antibiotic-resistant Staphylococcus aureus, a strain of bacteria that can cause staph infections that are difficult to treat with traditional anti-infection drugs such as methicillin, can be caught when you take a dip in ocean water, said Dr. Lisa Plano of the University of Miami's Miller School of Medicine.

MRSA stands for methicillin-resistant Staphylococcus aureus, or multiple-resistant Staphylococcus aureus. It has become a deadly and growing problem in hospitals in recent years.

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Last Week's Satellite Collision Is Now Called A "Catastrophic Event"

Image: This image provided by the European Space Agency shows and artist impression of catalogued objects in low-Earth orbit viewed over the Equator. Scientists are keeping a close eye on orbital debris created when two communications satellites _ one American, the other Russian _ smashed into each other hundreds of miles above Siberia Feb. 10, 2009. (AP Photo/ESA)

"Catastrophic" Space Crash Spews Debris -- CBS News

Space Junk Generated From Satellite Collision Could Threaten Other Satellites For 10,000 Years, Experts Say

(CBS/AP) The crash of two satellites has generated an estimated tens of thousands of pieces of space junk that could circle Earth and threaten other satellites for the next 10,000 years, space experts said Friday.

One called the collision "a catastrophic event" that he hoped would force the new U.S. administration to address the issue of debris in space.

Russian Mission Control chief Vladimir Solovyov said Tuesday's smashup of a derelict Russian military satellite and a working U.S. Iridium commercial satellite occurred in the busiest part of near-Earth space - some 500 miles (800 kilometers) above Earth.

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Our Eyes Constantly Flicker To Stop Us Going Blind, Experts Discover

Scientists believe flickering eye movements 'refresh' images on the retina

From The Daily Mail:

Unconscious flickering eye movements once thought to be random 'motor noise' may in fact be necessary to stop us going blind, a study has shown.

The imperceptible jumps and jiggles known as 'microsaccades' mean that a really steady stare is impossible.

Even when trying to fix a gaze on a stationary target, the eyes are always moving.

Experts have long dismissed these movements as the accidental result of spurious nerve signals. But new research shows they are actively controlled by the same brain region used to scan newspaper columns or track a moving object.

Scientists now think microsaccades provide a vital function by 'refreshing' images on the retina which would otherwise fade away.

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World's Greatest Hacker Says Obama's BlackBerry Can Be Breached

Jan. 29: President Obama checks his BlackBerry as he walks along the West Wing Colonnade towards the Oval Office at the White House in Washington. Photo AP

From FOX News:

There's a new "holy grail" for hackers — President Obama's super-secure BlackBerry.

Despite warnings from his advisers, the president insisted on keeping his beloved PDA, which now has specially designed superencrypting security software.

But that just makes cracking into it more challenging — and, yes, it can be done, says the world's most famous hacker.

"It's a long shot, but it's possible," Kevin Mitnick told FOXNews.com. "You'd probably need to be pretty sophisticated, but there's people out there who are."

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Biotechnology's Potential Barely Exploited: Scientists

This picture released by the Seoul research institute Maria BioTech shows human embryonic stem cells. New research tools will bring a boom in biotechnology that will unlock the enormous potential of using synthetic life to cure disease and develop environmentally friendly fuels, scientists say. (AFP/HO/File)

From Yahoo News/AFP:

CHICAGO (AFP) – New research tools will bring a boom in biotechnology that will unlock the enormous potential of using synthetic life to cure disease and develop environmentally friendly fuels, scientists say.

"If you look at all the things biology can do with technology, we have not yet scratched the surface," said Drew Endy, assistant professor of bioengineering at Stanford University.

The past 35 years of biotech development have introduced a number of "tremendous applications," particularly in the area of bioengineered drugs, Endy said at the annual conference of the American Association for the Advancement of Science here.

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Doomed: Why Wikipedia Will Fail

From Ars Technica:

A cyberlaw professor argues that Wikipedia is doomed. The online encyclopedia will need to choose between being "high quality" and "open," but both choices are fraught with risk.

Law professor Eric Goldman loves Wikipedia, but he's also convinced that the site contains the "seeds of its own destruction." In other words, not to put too fine a point upon it, Wikipedia will fail.

Goldman made his provocative point at the Silicon Flatirons conference this weekend in Boulder, Colorado, standing at a heavy wooden podium in a multiuse room that had been donated to the University of Colorado by a graduating class back in the 1960s. Those students could not have foreseen Wikipedia at the time, but by 2008, everyone gathered in that room—from corporate vice presidents to think tank bosses to academics—had made use of the collaborative online encyclopedia.

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The Secret of Successful Kissing

Droolly Smooches! : RebeccaJBuckley (CC Licensed)

From PopSci:

It's in the drool, fool.

Can drooling make you a better kisser? Scientific evidence suggests that wet, sloppy smooches pack a bigger biochemical punch than dry kisses and thus may be more likely to lead to sex and reproduction, says Rutgers University researcher Helen Fischer, who spoke today at the AAAS conference in Chicago.

Men are particularly prone to sloppy kissing, she notes, possibly because males tend to have a poor sense of smell and taste and aggressive face sucking may be an unconscious effort to gauge a partner's estrogen levels and fertility cycle. It may also be an unwitting effort to transmit testosterone, which can be found in saliva and can increase sexual attraction. Alternatively, it may also be just plain gross. (That would be my unscientific conclusion.)

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Galaxy Has 'Billions Of Earths'

From The BBC:

There could be one hundred billion Earth-like planets in our galaxy, a US conference has heard.

Dr Alan Boss of the Carnegie Institution of Science said many of these worlds could be inhabited by simple lifeforms.

He was speaking at the annual meeting of the American Association for the Advancement of Science in Chicago.

So far, telescopes have been able to detect just over 300 planets outside our Solar System.

Very few of these would be capable of supporting life, however. Most are gas giants like our Jupiter; and many orbit so close to their parent stars that any microbes would have to survive roasting temperatures.

But, based on the limited numbers of planets found so far, Dr Boss has estimated that each Sun-like star has on average one "Earth-like" planet.

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Scientists Map the 10 Billion Neurons of Human Cerebral Cortex & Find A Central Switchboard

Image from The Daily Galaxy

From The Daily Galaxy:

The study of the human brain is one of the most fascinating, and incredibly meta, subjects in existence. The almost Escherian experiments of one brain studying another brain (which is thinking about being studied by the first) have up to now been held back by one thing: the brain's owner is kind of using it so you can't poke too hard. Now a new scanning technique has allowed scientists to probe deeper than ever into the secrets of the mind.

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Study Takes Step Toward Erasing Bad Memories

Image from The Daily Galaxy:

From Zimbio:

LONDON, Feb 15 (Reuters) - A widely available blood pressure pill could one day help people erase bad memories, perhaps treating some anxiety disorders and phobias, according to a Dutch study published on Sunday.

The generic beta-blocker propranolol significantly weakened people's fearful memories of spiders among a group of healthy volunteers who took it, said Merel Kindt, a psychologist at the University of Amsterdam, who led the study.

"We could show that the fear response went away, which suggests the memory was weakened," Kindt said in a telephone interview.

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Tailplane Icing (Video)

NASA figured it all out 11 years ago. The link is HERE.

Do We Need A New Internet?

Image by Guy Hoffman

From The New York Times:

Two decades ago a 23-year-old Cornell University graduate student brought the Internet to its knees with a simple software program that skipped from computer to computer at blinding speed, thoroughly clogging the then-tiny network in the space of a few hours.

The program was intended to be a digital “Kilroy Was Here.” Just a bit of cybernetic fungus that would unobtrusively wander the net. However, a programming error turned it into a harbinger heralding the arrival of a darker cyberspace, more of a mirror for all of the chaos and conflict of the physical world than a utopian refuge from it.

Since then things have gotten much, much worse.

Bad enough that there is a growing belief among engineers and security experts that Internet security and privacy have become so maddeningly elusive that the only way to fix the problem is to start over.

What a new Internet might look like is still widely debated, but one alternative would, in effect, create a “gated community” where users would give up their anonymity and certain freedoms in return for safety. Today that is already the case for many corporate and government Internet users. As a new and more secure network becomes widely adopted, the current Internet might end up as the bad neighborhood of cyberspace. You would enter at your own risk and keep an eye over your shoulder while you were there.

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Mini Nuclear Plants In Alaska

The Toshiba 4S (Super-Safe, Small and Simple) nuclear power plant is designed to be delivered, installed, and carried away 30 years later. It may meet the needs of remote sites around the world. Adapted by Morgan Ryan and Stephanie Freese from image provided by Toshiba Corporation.

A Nuke on the Yukon?

Mini-nukes arrive at the regulatory gate. Will they get through?

Morgan Ryan

Galena, Alaska, could be the type specimen for remoteness. A tiny town of about 700 on a bend of the Yukon River, it has no roads in and depends on the river for food, fuel and supplies. The river is frozen eight to nine months of the year. Galena residents pay three times the national average per kilowatt hour for diesel-generated electricity. Alternative energy would have special appeal for Galena, but with an evening that stretches 20 hours in the winter, solar is out. With the help of Toshiba and its American holding, Westinghouse, Galena is thinking nuclear.

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Camouflaging Of Viral DNA Could Be Crucial Step In Progression Of Cancers

From Science Daily:

ScienceDaily (Feb. 14, 2009) — An estimated 15% of cancer cases can be linked to a viral infection, however the biological changes that cause some asymptomatic carriers of a virus to develop full-blown tumors are not well understood. In a study published online in Genome Research, scientists have mapped a chemical modification of DNA in three oncogenic viruses (Epstein-Barr, human papilloma virus, and hepatitis B virus) and found that the viral genome undergoes critical changes during the progression of disease, with implications for the development of new methods of prevention, diagnosis, and treatment.

Worldwide, most people are already infected with the Epstein-Barr virus, and millions are infected with the human papilloma virus and the hepatitis B virus. Many of these individuals will develop disease, and some will eventually develop a viral-related cancer such as lymphoma, liver cancer, or cervical cancer. Understanding how infections of viruses such as these can progress to cancer in some individuals is essential to the development of new methods to attack the virus and prevent malignancies.

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Scientists Warn Of First Ever Case Of Human Mad Cow Disease From Blood Plasma

From The Telegraph:

The first case of a person being infected with the human form of mad cow disease after receiving contaminated blood plasma has been identified by scientists.

The man was one of thousands of haemophiliacs who received blood plasma transfusions in the years before strict controls were brought in to eliminate the spread of variant Creutzfeldt-Jakob disease (vCJD).

Until now, scientists had maintained that the 4,000 people who may have received plasma from infected donors were at very low risk of developing the fatal brain disease. Warnings were issued to them as a "highly precautionary measure".

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New Artificial DNA Points to Alien Life

From Live Science:

CHICAGO — A strange, new genetic code a lot like that found in all terrestrial life is sitting in a beaker full of oily water in a laboratory in Florida, a scientist said today, calling it the first example of an artificial chemical system that is capable of Darwinian evolution.

The system is made of the four molecules that are the basic building blocks of our DNA along with eight synthetic modifications of them, said biochemist Steven A. Benner of the Foundation for Applied Molecular Evolution in Gainesville.

The main difference between the synthetic molecules and those that make up conventional DNA is that Benner's molecules cannot make copies of themselves, although that is just "a couple of years" away, he said.

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