From Popular Science:
Imagine you’re driving across the Mojave Desert, and somewhere in the middle of absolutely nowhere you realize that the next gas station is further away than your car can travel on its current supply of gasoline. What next? That’s the problem NASA mission planners are facing as the agency's supply of plutonium-238, the fuel used to power deep space probes like Cassini and surface scouts like the upcoming Mars Science Laboratory, are dwindling. Unfortunately, that leaves NASA in a pretty tight spot: we’ve depleted our reserves of plutonium-238, and there isn’t anywhere to refuel ahead on the horizon either.
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