Total Recall Achieved

From Scientific American:

Activating a small fraction of neurons triggers complete memory.

Just as a whiff of pumpkin pie can unleash powerful memories of holiday dinners, the stimulation of a tiny number of neurons can evoke entire memories, new research in mice suggests.

Memories are stored in neurons distributed across a host of brain regions. When something triggers a memory, that diffuse information is immediately and cohesively reactivated, but it's unclear how the circuit gets kicked into full gear.

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Learning A Musical Instrument Helps To Boost Children's Memory

Children playing musical instruments in Scotland.
Photograph: Murdo Macleod/Murdo Macleod

From Times Online:

Learning a musical instrument is beneficial for children’s behaviour, memory and intelligence, a government-commissioned study suggests.

Research found that learning to play an instrument enlarges the left side of the brain, enhancing pupils’ power of memory by almost 20 per cent.

Susan Hallam, of the University of London’s Institute of Education, carried out the research as part of a drive to encourage more children to take up a musical instrument.

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Abruptly Forgotten: Working Memory Disappears In A Blink

From Scientific American:

Certain memories die suddenly rather than fading away.

When you go from bed to bathroom on a dark night, a quick flick of the lights will leave a lingering impression on your mind’s eye. For decades evidence suggested that such visual working memories—which, even in daylight, connect the dots to create a complete scene as the eyes dart around rapidly—fade gradually over the span of several seconds. But a clever new study reported in the journal Psychological Science finds that such memories actually stay sharp until they are suddenly lost.

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Scientists Develop Nasal Spray That Improves Memory

Good news for procrastinating students: a nasal spray developed by a team of German scientists promises to give late night cram sessions a major boost, if a good night's sleep follows. (Credit: iStockphoto/Ana Blazic)

From Science Daily:

ScienceDaily (Oct. 2, 2009) — Good news for procrastinating students: a nasal spray developed by a team of German scientists promises to give late night cram sessions a major boost, if a good night's sleep follows. In a research report featured as the cover story of the October 2009 print issue of The FASEB Journal, these scientists show that a molecule from the body's immune system (interleukin-6) when administered through the nose helps the brain retain emotional and procedural memories during REM sleep.

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Microsoft Researcher Converts His Brain Into 'E-Memory'

Photo: Gordon Bell wearing a SenseCam, which automatically records photos throughout the day.

From CNN:

(CNN) -- For the past decade, Microsoft researcher Gordon Bell has been moving the data from his brain onto computers -- where he knows it will be safe.

Sure, you could say all of us do this to some extent. We save digital pictures from family events and keep tons of e-mail.

But Bell, who is 75 years old, takes the idea of digital memory to a sci-fi-esque extreme. He carries around video equipment, cameras and audio recorders to capture his conversations, commutes, trips and experiences.

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Researchers Unravel Brain's Wiring To Understand Memory

From McClatchy News:

WASHINGTON — Using a powerful microscope, Karel Svoboda, a brain scientist at the Janelia Farm Research Campus in Ashburn, Va., peers through a plastic window in the top of a mouse's head to watch its brain's neurons sprout new connections — a vivid display of a living brain in action.

Ryan LaLumiere, a neurologist at the Medical University of South Carolina in Charleston, trains cocaine-addicted rats to suppress their craving — a technique he says may help human addicts.

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Direct Evidence Of Role Of Sleep In Memory Formation Is Uncovered

For the first time, researchers have pinpointed the mechanism that takes place during sleep that causes learning and memory formation to occur. (Credit: iStockphoto/Mads Abildgaard)

From Science Daily:

ScienceDaily (Sep. 16, 2009) — A Rutgers University, Newark and Collége de France, Paris research team has pinpointed for the first time the mechanism that takes place during sleep that causes learning and memory formation to occur.

It’s been known for more than a century that sleep somehow is important for learning and memory. Sigmund Freud further suspected that what we learned during the day was “rehearsed” by the brain during dreaming, allowing memories to form. And while much recent research has focused on the correlative links between the hippocampus and memory consolidation, what had not been identified was the specific processes that cause long-term memories to form.

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Ready Or Not, Time To Grapple With E-Memory

MyLifeBits can be used to catalog and search personal archives.
(Credit: Dutton Books)

From CNET:

Just because Gordon Bell and Jim Gemmell are way out there on the nerd spectrum, don't ignore what they have to say in their new book, "Total Recall."

The Microsoft researchers obsessively record e-mails, photos, videos, phone calls, health records, financial transactions, Web site visits, and everything else they can in an attempt to electronically compensate for the fallibility of their own biological memories. Before you recoil at the prospect of letting your own life become this digitally augmented, though, consider that it will be whether you want it or not.

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You Can Believe Your Eyes: New Insights Into Memory Without Conscious Awareness

New findings may shed light on the role of the hippocampus in memory and awareness, as they suggest that even when people fail to recollect a past event, the hippocampus might still support an expression of memory through eye movements. (Credit: iStockphoto)

From Science Daily:

ScienceDaily (Sep. 10, 2009) — Scientists may have discovered a way to glean information about stored memories by tracking patterns of eye movements, even when an individual is unable (or perhaps even unwilling) to report what they remember. The research, published by Cell Press in the September 10th issue of the journal Neuron, provides compelling insight into the relationship between activity in the hippocampus, eye movements, and both conscious and unconscious memory.

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Memories Exist Even When Forgotten, Study Suggests

Jeff Johnson of the UCI Center for the Neurobiology of Learning & Memory and colleagues discovered that a person's brain activity while remembering an event is very similar to when it was first experienced, even if specifics can't be recalled. Johnson says brain imaging shines a "searchlight" into the brain. (Credit: Daniel A. Anderson / University Communications)

From Science Daily:

ScienceDaily (Sep. 10, 2009) — A woman looks familiar, but you can't remember her name or where you met her. New research by UC Irvine neuroscientists suggests the memory exists – you simply can't retrieve it.

Using advanced brain imaging techniques, the scientists discovered that a person's brain activity while remembering an event is very similar to when it was first experienced, even if specifics can't be recalled.

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Memory Scientists Say: All Is Not Forgotten

fMRI Brain Activity Jan Hardenbergh

From Popular Science:

Unless you are this woman, you probably have a long mental list of moments and facts you wish you could remember -- but for the life of you, you can't. To use a personal example, I periodically Google the words "yellow house Berlin," hoping to produce the name of that one hostel I lived in for a summer in college; alas, no success yet. The good news, though, is that while such memories may be currently inaccessible, they're not entirely gone, and could theoretically be retrieved, according to new brain imaging research from the University of California, Irvine.

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Is Quantum Mechanics Selectively Erasing Our Memory?

Entropy At Work: One liquid diffusing into another is an
example of an increase in entropy, or randomness.

From Popular Science:

In a paper published last week, MIT physicist Lorenzo Maccone hypothesizes that, yes, quantum physics is messing with our minds. The laws of physics work just as well if time is running forwards or backwards. But we all seem to experience time running in only one direction, and in the same direction as everyone else -- a mystery of physics that's yet to be solved.

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Neuroscientist's Research Holds Clues About Short-Term Memory

George Mason graduate student John Fedota, right, takes the kind of memory test that helped identify Subject 7 at Raja Parasuraman's lab. "Ninety percent of neuroscience work has been done on animals. The techniques are all invasive and cannot be used on humans. But in the last 20 years we’ve developed noninvasive techniques to study human brain functions," says Parasuraman.

From Popular Mechanics:

What is a cognitive superstar? One grad student's exceptional brain could help settle the debate of nature versus nurture. For a full interview with neuroscientist Raja Parasuraman.

Last year, Raja Parasuraman was conducting a study of brain function among 650 participants at George Mason University in Virginia, when he stumbled across what he calls a “cognitive superstar.” The university professor studies neuroergonomics—a merger of neuroscience, the study of the brain, with ergonomics, the study of how to design systems and tech-nologies to be more compatible with users. Parasuraman hooks subjects to MRI, EEG and other brain scanners while conducting memory and attention tests to see what parts of the brain activate.

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Why It Is Easy To Encode New Memories But Hard To Hold Onto Them

Activated PAK (red) gathers at synapses (green), and might help consolidate fresh memories. (Credit: Rex, C.S., et al. 2009. J. Cell Biol. doi:10.1083/jcb.200901084)

From Science Daily:

ScienceDaily (July 14, 2009) — Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 issue of the Journal of Cell Biology, Rex et al. reveal that LTP's actin reorganization occurs in two stages that are controlled by different pathways, a discovery that helps explain why it is easy to encode new memories but hard to hold onto them.

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Caffeine Reverses Memory Impairment In Mice With Alzheimer's Symptoms

Coffee drinkers may have another reason to pour that extra cup. When aged mice bred to develop symptoms of Alzheimer's disease were given caffeine -- the equivalent of five cups of coffee a day -- their memory impairment was reversed. (Credit: iStockphoto/Royce DeGrie)

From Science Daily:

ScienceDaily (July 6, 2009) — Coffee drinkers may have another reason to pour that extra cup. When aged mice bred to develop symptoms of Alzheimer's disease were given caffeine – the equivalent of five cups of coffee a day – their memory impairment was reversed, report University of South Florida researchers at the Florida Alzheimer's Disease Research Center.

Back-to-back studies published online July 6 in the Journal of Alzheimer's Disease, show caffeine significantly decreased abnormal levels of the protein linked to Alzheimer's disease, both in the brains and in the blood of mice exhibiting symptoms of the disease. Both studies build upon previous research by the Florida ADRC group showing that caffeine in early adulthood prevented the onset of memory problems in mice bred to develop Alzheimer's symptoms in old age.

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Coming Soon: Photographic Memory In A Pill?

RGS-14: Will you remember what this protein looks like 2 months from now?

From Popsci.com:

Scientists isolate a protein that significantly increases visual recall.

Wish you had a photographic memory? Well, Encyclopedia Brown, drugs may amp your brain up to that point soon. A group of Spanish scientists claim to have singled out a protein that can extend the life of visual memory significantly. When the production of the protein was boosted in mice, the rodents' visual memory retention increased, from about an hour to almost 2 months.

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First Image Of Memories Being Made

The increase in green fluorescence represents the imaging of local translation at synapses during long-term synaptic plasticity. (Credit: Science)

From Science Daily:

ScienceDaily (June 19, 2009) — The ability to learn and to establish new memories is essential to our daily existence and identity; enabling us to navigate through the world. A new study by researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University and University of California, Los Angeles has captured an image for the first time of a mechanism, specifically protein translation, which underlies long-term memory formation.

The finding provides the first visual evidence that when a new memory is formed new proteins are made locally at the synapse - the connection between nerve cells - increasing the strength of the synaptic connection and reinforcing the memory. The study published in Science, is important for understanding how memory traces are created and the ability to monitor it in real time will allow a detailed understanding of how memories are formed.

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Electronic Memory Chips That Can Bend And Twist

Image: Electronic memory chips may soon gain the ability to bend and twist like this one. (Credit: NIST)

From Science Daily:

ScienceDaily (June 3, 2009) — Electronic memory chips may soon gain the ability to bend and twist as a result of work by engineers at the National Institute of Standards and Technology (NIST). As reported in the July 2009 issue of IEEE Electron Device Letters, the engineers have found a way to build a flexible memory component out of inexpensive, readily available materials.

Though not yet ready for the marketplace, the new device is promising not only because of its potential applications in medicine and other fields, but because it also appears to possess the characteristics of a memristor, a fundamentally new component for electronic circuits that industry scientists developed in 2008. NIST has filed for a patent on the flexible memory device (application #12/341.059).

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New Memory Material May Hold Data For One Billion Years

Scientists are reporting an advance toward a memory device capable of storing data for more than one billion years. (Credit: The American Chemical Society)

From Science Daily:

ScienceDaily (May 26, 2009) — Packing more digital images, music, and other data onto silicon chips in USB drives and smart phones is like squeezing more strawberries into the same size supermarket carton. The denser you pack, the quicker it spoils. The 10 to 100 gigabits of data per square inch on today's memory cards has an estimated life expectancy of only 10 to 30 years. And the electronics industry needs much greater data densities for tomorrow's iPods, smart phones, and other devices.

Scientists are reporting an advance toward remedying this situation with a new computer memory device that can store thousands of times more data than conventional silicon chips with an estimated lifetime of more than one billion years. Their discovery is scheduled for publication in the June 10 issue of the American Chemical Society's Nano Letters, a monthly journal.

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Memory Pill That Could Help Students And Alzheimer's Patients Being Developed

A pill that could make memories 'stick' is being developed by scientists in a study that could help students revising for exams and patients with brain disorders Photo: GETTY

From The Telegraph:

A pill that could make memories "stick" is being developed by scientists in a study that could help students revising for exams and patients with brain disorders such as Alzheimer's disease.

Researchers, looking into obesity, discovered that fatty foods not only send feelings of fullness to the brain but they also trigger a process that consolidates long term memories.

It believed that this is an evolutionary tool that enabled our distant ancestors to remember where rich sources of food were located.

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