Early U.S. Flu Season Accelerates

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Early Flu Season Accelerates; No Peak Yet, CDC Says -- NBC 

The nation’s early flu season continued to grow in the U.S. this week, with no sign yet of a peak in the spread of coughing, achy, feverish illness, health officials said Friday.

"I think we're still accelerating," said Tom Skinner, a CDC spokesman.

Twenty-nine states and New York City reported high levels of flu activity, up from 16 states and NYC the previous week. Flu was widespread in 41 states, up from 31 states, according to the latest figures from the Centers for Disease Control and Prevention.

As of the week ending Dec. 29, 2,257 people had been hospitalized with flu, and 18 children had died from complications of the illness, CDC reported.

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My Comment: Take the flu shot and washing my hands is my remedy.

Breakthrough Flu Drug Might Already Exist

Image: Structurally sound: The neuraminidase protein of the H1N1 virus is particularly adept at mutating to avoid attack. In this crystal structure, the mutations that allow it to resist Tamiflu and other antiviral drugs are visible as multicolored stick structures. Credit: Dani

From Technology Review:

Fragments of known drugs could lead to a more robust antiviral for H1N1 and other flu variants.

The flu virus is a wily target, constantly mutating to avoid attack from the immune system and from antiviral drugs like Tamiflu. But in research presented Sunday at the annual meeting of the American Society for Cell Biology (ASCB) in San Diego, scientists announced a new method for fighting pandemic influenzas such as H1N1 (swine) and H5N1 (avian).

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Brazil Finds New Strain Of H1N1 Virus

From Breitbart/AFP:

Brazilian scientists have identified a new strain of the H1N1 virus after examining samples from a patient in Sao Paulo, their institute said Tuesday.

The variant has been called A/Sao Paulo/1454/H1N1 by the Adolfo Lutz Bacteriological Institute, which compared it with samples of the A(H1N1) swine flu from California.

The genetic sequence of the new sub-type of the H1N1 virus was isolated by a virology team lead by one of its researchers, Terezinha Maria de Paiva, the institute said in a statement.

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WHO: Swine Flu Pandemic Has Begun, 1st In 41 Years

Swine flu has spread in Australia since a ship with infected passengers there has docked.
(HO/Reuters)

From AP:

GENEVA (AP) — The World Health Organization has told its member nations it is declaring a swine flu pandemic — the first global flu epidemic in 41 years.

The move came Thursday as infections climbed in the United States, Europe, Australia, South America and elsewhere.

In a statement sent to member countries, WHO says it decided to raise the pandemic alert level from phase 5 to 6, meaning that a global outbreak of swine flu has begun. The decision was made after the U.N. health agency held an emergency meeting on swine flu with its experts.

THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP's earlier story is below.

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More News On WHO Declaring A Pandemic

WHO 'declares swine flu pandemic' -- BBC
WHO declares swine flu pandemic -- AFP
WHO tells some members world is in swine flu pandemic -- CBC
The Pandemic is Now -- NPR
Swine Flu Now Declared A Global Pandemic -- SKY News
WHO declares global swine flu pandemic -- Times Online

Is This A Pandemic? Define ‘Pandemic’

TERMINOLOGY It is not often clear when the spread of a disease, such as cholera, for which a boy was being treated in Congo, becomes a pandemic. Uriel Sinai/Getty Images

From The New York Times:

After decades of warnings about the inevitability of another pandemic of influenza, it is astonishing that health officials have failed to make clear to the public, even to many colleagues, what they mean by the word pandemic.

Generations of people have used the term to describe widespread epidemics of influenza, cholera and other diseases. But as the new H1N1 swine influenza virus spreads from continent to continent, it is clear that a useful definition is far more complicated and elusive than officials had thought.

And what is at stake is far more than an exercise in semantics. A clear understanding of the term is central to the World Health Organization’s six-level staging system for declaring a pandemic, which in turn informs countries when to set their control efforts in motion.

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WHO Official Says World Edging Towards Pandemic

A picture shoes an airport thermal camera system monitoring the body heat of passengers arriving from abroad is displayed at Sofia airport in this April 29, 2009 file photo. REUTERS/Stoyan Nenov/Files

From Reuters:

GENEVA (Reuters) - The spread of H1N1 flu in Australia, Britain, Chile, Japan and Spain has nudged the world closer to a pandemic, the World Health Organisation said on Tuesday.

The newly-discovered strain had caused more infections than seasonal influenza at the start of Chile's flu season, raising concern about how it would spread in the southern hemisphere, according to Keiji Fukuda, the WHO's acting assistant director-general.

The virus has mainly affected people aged below 60 and caused 117 deaths worldwide, including some otherwise healthy people, he said. For now, the WHO's pandemic scale remained at the second-highest level but the threshold may soon be crossed.

"Globally we believe that we are at Phase 5 but we are getting closer to Phase 6," Fukuda told journalists. "The future impact of this infection has yet to unfold."

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Innards of H1N1 Virus Resemble 'Flu Sausage'

From Live Science:

On March 28, one month before news of the swine flu outbreak headlined worldwide, a nine-year-old girl in Imperial County, California, ran a fever of 104.3°F. She had not rolled up her sleeve for this year’s flu vaccine, but that day she opened her mouth and stuck out her tongue for a cotton swab that scooped up mucous samples from her throat. Her mucus arrived at the Naval Health Research Center in San Diego where technicians tested it and classified the virus in it as “unsubtypable” influenza A – it was something new.

She recovered.

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New Way Of Treating The Flu

Dr. Robert Linhardt's new compound (green spheres) blocks both the N (pink spikes) and H (blue spikes) portion of the flu virus. The compound prevents the infection of the cell and the spread of the flu to other cell like no other compound before. (Credit: Melissa Kemp/Rensselaer Polytechnic Institute)

From Science Daily:

ScienceDaily (May 20, 2009) — What happens if the next big influenza mutation proves resistant to the available anti-viral drugs? This question is presenting itself right now to scientists and health officials this week at the World Health Assembly in Geneva, Switzerland, as they continue to do battle with H1N1, the so-called swine flu, and prepare for the next iteration of the ever-changing flu virus.

Promising new research announced by Rensselaer Polytechnic Institute could provide an entirely new tool to combat the flu. The discovery is a one-two punch against the illness that targets the illness on two fronts, going one critical step further than any currently available flu drug.

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5 Ways To Protect Yourself (And Others) From Swine Flu

Photo: GOOD OLD SOAP AND WATER: Experts say frequent hand washing is one of the best ways to defend against swine flu. ISTOCKPHOTO/ALANDJ

From Scientific American:

Swine flu has yet to escalate into a global pandemic, but here's what to do if it does.

Experts say that the steps you should take to shield yourself from swine flu are not much different than those you might take to ward off seasonal flu.

1. Don't touch your face
Above all, keep your hands away from your eyes, mouth and nose, all of which serve as pathways for the virus to enter your respiratory tract, says Allison Aiello, an epidemiologist at the University of Michigan School of Public Health in Ann Arbor.

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'Worst-Case' Scenario For Flu Estimated

This map shows the projected number of H1N1 "swine flu" cases in the United States at the county level, 28 days from now. Credit: Christian Thiemann, Rafael Brune, and Alejandro Morales Gallardo/Northwestern University

For Live Science:

There will be about 1,700 U.S. cases of the new H1N1 flu, aka "swine flu," in the next four weeks under a worst-case scenario, according to a research team's new simulations.

And a second team working independently, about 200 miles away, on exactly the same question came up with a similar forecast.

As of Thursday, there were 109 lab-confirmed U.S. cases of the new influenza, according to the World Health Organization, which earlier this week raised the risk level of the influenza to one stage below pandemic because the virus is being transmitted within at least two countries in one region of the world. A full pandemic — the virus is also being transmitted within a third country in a different region — is considered imminent.

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Scientists Close In On 'Universal' Vaccine For Flu: Study

From Breitbart/AFP:

Scientists on Sunday unveiled lab-made human antibodies that can disable several types of influenza, including highly-lethal H5N1 bird flu and the "Spanish Flu" strain that killed tens of millions in 1918.

Tested in mice, the antibodies work by binding to a previously obscure structure in the flu virus which, when blocked, sabotages the pathogen's ability to enter the cell it is trying to infect, according to the study.

Because this structure -- described by one scientist as a "viral Achilles' heel" -- is genetically stable and has resisted mutation over time, the antibodies are effective against many different strains.

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Common Cold DNA Deciphered, Congestion Continues

Structure of the human rhinovirus capsid. Credit: of J.-Y. Sgro, UW-Madison

From Live Science:

Snifflers of the world rejoice: Scientists are one step closer to finding effective treatments for the common cold now that researchers have deciphered the genetic code of the ubiquitous virus.

While a full-blown cure for the common cold is not expected anytime soon, the mapping of the human rhinovirus's genetic blueprint will help scientists better understand and combat this highly contagious pathogen. In the meantime, there are always ways to help keep yourself from succumbing to the coughs and congestion.

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Cure For The Common Cold?

Colds are caused by a virus and can occur year-round. The common cold generally involves a runny nose, nasal congestion, and sneezing. Other symptoms include sore throat, cough, and headache. A cold usually lasts about 7 days, with perhaps a few lingering symptoms such as a cough for another week. (Photo from Medline Plus)

Hope For Common Cold Treatment -- The Telegraph

Hopes for a treatment for common cold have been raised after scientists discovered how it causes symptoms such as sneezing and a runny nose.

The characteristic effects of a cold are not brought about directly by the virus but by its ability to turn the body's own defences against itself, scientists have found.

Up to half of common colds are caused by various strains of the human rhinovirus and new research has shown the bug triggers a domino effect where the body's own defences over-react causing the familiar symptoms.

The findings could result in treatments for common colds caused by rhinovirus which strike hundreds of thousands of people each year in the UK.

Current treatments only work on allievating the symptoms rather than tackling the cause of the cold.

A team at the University of Calgary, in Canada, took samples from the noses of 35 volunteers, 17 of whom had been infected with a rhinovirus.

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Step Aside, Chicken Soup: Eight Cold Elixirs

From ABC News:

Spanning the Globe in Search of Alternative Home Remedies for the Common Cold
No matter where you live or what language you speak, the symptoms of a coldare understood the world over -- no translation required: Your throat feels sore; your nose runs; you might cough or sneeze; and your body aches.

It's time to crawl under the covers and get the extra rest you need.

But a cold virus will need some coaxing to hit the road. Colds rarely make a quick exit and usually take about a week to run their course.

That's where the time-honored tradition of folk medicine comes into play.

Faced with a cold and a lack of modern medicine, our ancestors turned to nature for its treatments. And throughout the world, parts of plants -- the roots, stems, leaves, fruits and flowers -- are used to ease a cold and its symptoms.

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Universal Flu Vaccine Enters Clinical Trials

From Futurismic:

It’s that time of year again, when doctors recommend everyone from children to old folks get jabbed with the latest influenza vaccine that may or may not actually be effective against this year’s strain. And it’s that time of year again when people start worrying about the presumably inevitable next great ‘flu pandemic, which many fear could be coming as avian influenza continues to mutate.

Wouldn’t it be great if you could just get a single shot that would protect against multiple types…including the possible bird ‘flu pandemic?

Clinical trials of just such a vaccine have begun at Oxford University, led by Dr. Sarah Gilbert of the Jenner Institute. (Via PhysOrg.)

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