Nicotine May Have More Profound Impact Than Previously Thought

Researchers have found that the alpha-7 receptor, a site known to bind with nicotine, interacts with 55 different proteins. Nicotine may affect bodily processes -- and perhaps the actions of other commonly used drugs -- more broadly than was previously thought. (Credit: Hawrot Lab/Brown University)

From Science Daily:

ScienceDaily (Apr. 4, 2009) — Nicotine isn't just addictive. It may also interfere with dozens of cellular interactions in the body, new Brown University research suggests.

Conversely, the data could also help scientists develop better treatments for various diseases. Pharmaceutical companies rely on basic research to identify new cellular interactions that can, in turn, serve as targets for potential new drugs.

"It opens several new lines of investigation," said lead author Edward Hawrot, professor of molecular science, molecular pharmacology, physiology and biotechnology at Brown University.

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