Image: National Institute of General Medical SciencesFrom Discover Magazine:
For decades, RNA was seen as a simple slave to DNA. Newer research shows it has an active and critical role in every disease from Alzheimer's to cancer.
One of the great revolutions in modern science rests on the elongated backside of a grotesque, mutant worm. Inexpensive and easy to manipulate in the lab, Caenorhabditis elegans develops from egg to adult in three days and produces a few hundred offspring three days after that. Virtually all of the worms are hermaphrodites, containing both male and female sex organs and capable of making sperm and eggs, so each creature can fertilize itself. And because the worm is transparent and the adult has only 959 cells, development of every stage from egg to adult can be observed under the microscope and documented with near perfect detail while the worm is alive, an achievement accomplished in the 1970s by Sidney Brenner, a University of Cambridge researcher and legend in the field.
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