Friday, October 2, 2009

A Genetic Fountain Of Youth

Aging machines: Mice lacking a functional version of the protein S6 kinase 1, an important regulator of the body's response to nutrient availability, live longer and healthier lives than their normal counterparts. The mouse on the left lacks the protein. Credit: George Thomas, University of Cincinnati

From Technology Review:

Researchers have identified a genetic tweak that can slow aging in mice.

By disabling a gene involved in an important biochemical signaling pathway, scientists have discovered a way to mimic the well-known anti-aging benefits of caloric restriction, allowing mice to live longer and healthier lives. This finding, published online today in Science, offers a promising drug target for combating the many health problems associated with aging.

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