PET scans can detect the decline in glucose metabolism associated with decreased cognitive function, particularly in the temporal and parietal lobes located on the sides and the back of the brain, the regions associated with memory formation and language. UC Berkeley researchers are finding that brain imaging shows promise as a method of detecting early signs of Alzheimer's disease. On the left is a PET scan showing normal levels of glucose metabolism, indicated in yellow and red. The levels of glucose metabolism in the brain are decreased in patients with mild cognitive impairment (middle) and with Alzheimer's disease (right). (Credit: Cindee Madison and Susan Landau, UC Berkeley)From Science Daily:
ScienceDaily (July 15, 2009) — A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer's disease.
The research found that among 85 participants in the study with mild cognitive impairment, those with low scores on a memory recall test and low glucose metabolism in particular brain regions, as detected through positron emission tomography (PET), had a 15-fold greater risk of developing Alzheimer's disease within two years, compared with the others in the study.
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