Tuesday, December 30, 2008

Researchers Unlock Secrets Of 1918 Flu Pandemic

Policemen in Seattle wearing masks made by the Red Cross, during the influenza epidemic in a National Archives photo dated December 1918. (National Archives/Handout/Reuters)

From Yahoo News/Reuters:

WASHINGTON (Reuters) – Researchers have found out what made the 1918 flu pandemic so deadly -- a group of three genes that lets the virus invade the lungs and cause pneumonia.

They mixed samples of the 1918 influenza strain with modern seasonal flu viruses to find the three genes and said their study might help in the development of new flu drugs.

The discovery, published in Tuesday's issue of the Proceedings of the National Academy of Sciences, could also point to mutations that might turn ordinary flu into a dangerous pandemic strain.

Yoshihiro Kawaoka of the University of Wisconsin and colleagues at the Universities of Kobe and Tokyo in Japan used ferrets, which develop flu in ways very similar to humans.

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