The Good News and Bad News About MS

Multiple sclerosis attacks the myelin sheath that protects the nerve fiber.
(From How Stuff Works)

From Slate:

A miracle drug carries some serious risks.

Problem: Multiple sclerosis is a quite common and often terrible disease that most frequently attacks young adults—especially young women. There are two phases to MS—an early one and a late one. The early phase, in which the disease waxes and wanes, is caused when the body becomes allergic to its own tissues—specifically, white matter located in the brain and spinal cord. The inflammation caused by this allergy (which attacks the cells that form a protective layer surrounding the long, cablelike structures in nerve cells responsible for carrying electrical signals) causes the early symptoms (like visual disturbances or unsteadiness in walking) and primes the body for the second phase, in which irreversible damage is done to nerve cells, causing marked weakness, fatigue, loss of balance and coordination, bladder and bowel problems, and even changes in thinking and depression. There is a lot of evidence that if the early phase is managed in ways that decrease symptoms, the late phase, during which most of the irreversible damage happens, can be delayed and perhaps even prevented.

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