Image: Structurally sound: The neuraminidase protein of the H1N1 virus is particularly adept at mutating to avoid attack. In this crystal structure, the mutations that allow it to resist Tamiflu and other antiviral drugs are visible as multicolored stick structures. Credit: Dani
From Technology Review:
Fragments of known drugs could lead to a more robust antiviral for H1N1 and other flu variants.
The flu virus is a wily target, constantly mutating to avoid attack from the immune system and from antiviral drugs like Tamiflu. But in research presented Sunday at the annual meeting of the American Society for Cell Biology (ASCB) in San Diego, scientists announced a new method for fighting pandemic influenzas such as H1N1 (swine) and H5N1 (avian).
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