Mighty and MiniAfter 15 weeks a high-calorie diet, mice taking at least 500 mg of a new drug gained no weight. Meanwhile, their cholesterol levels improved and their running ability got a measurable boost. But don't run to the pharmacy: for now, this prescription is for rodents only.
From Discovery:
Nov. 7, 2008 -- Eat more than you should. Stay skinny. Run twice as far. Those are the big claims coming from a new drug study from Sirtris Pharmaceuticals, Inc., based in Cambridge, Mass. This latest study clears the way for human clinical trials of SRT1720, often touted as an "anti-aging pill."
SRT1720 activates the same receptor as the much-discussed resveratrol, the chemical in red wine that may slow some effects of aging. Both resveratrol and SRT1720 are being tested as a way to treat type-two diabetes first, and possibly other age-related diseases, later.
"We are very excited by these results," said Michelle Dipp of Sirtris. "These compounds are mimicking calorie restriction and exercise while lowering levels of glucose and insulin in mice. It's a game changer."
Read more ....
1 comment:
Since the Harvard resveratrol study by Dr. Sinclair was published in the journal Nature a flood of dubious companies have sprung up selling resveratrol. Many have no scientist, no labs, no quality control and no experience. One guy is making it in his house in Florida. Consumer Lab, an independent testing authority, evaluated the major brands and found many lacking in content and quality. The highest potency products that passed their evaluation were Biotivia, Transmax and Bioforte. A product by Life Extension Co. failed badly with only 26% of the claimed resveratrol. Another brand, Revatrol, had virtually no trans-resveratrol in its supplement. Revgenetics refused to provide samples for testing. The ConsumerLab test results are available on their web site.
Post a Comment