From Live Science:
When you put in hours at the gym, you expect to get fitter. It turns out, that assumption doesn't hold true for everyone. A new study suggests specific genes may determine, at least in part, how much we really benefit from exercise.
While "benefit from exercise" can mean plenty of things, from slimming down to boosting one's ability to complete a marathon, the researchers specifically looked at what is called VO2 max, or aerobic capacity. This is a measure of how much blood your heart pumps and how much oxygen your muscles consume when they constrict to, say, move your legs on a treadmill.
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