Tuesday, October 28, 2008

Scientists Find Way To Erase Memories In Mice

(Photo from Reuters)

From Reuters:

WASHINGTON (Reuters) - It seems like a movie plot, but scientists have developed a way to erase specific memories in mice while leaving others intact and not damaging the brain.

By manipulating levels of an important protein in the brain, certain memories can be selectively deleted, researchers led by neurobiologist Joe Tsien of the Medical College of Georgia reported in the journal Neuron.

While some experts have suggested there could be value in erasing certain memories in people such as wartime traumas, Tsien doubted this could be done as it was in mice. Tsien also questioned the wisdom of wiping out a person's memories.

"All memories, including the painful emotional memories, have their purposes. We learn great lessons from those memories or experiences so we can avoid making the same kinds of mistakes again, and help us to adapt down the road," Tsien said in a telephone interview on Thursday.

The study focused on a protein called alpha-CaMKII involved in learning and memory. The scientists manipulated alpha-CaMKII activity in the brains of genetically modified mice to influence the retrieval of short-term and long-term memories.

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