During Exercise, Human Brain Shifts Into High Gear On 'Alternative Energy'

From Science Daily:

ScienceDaily (Oct. 1, 2008) — Alternative energy is all the rage in major media headlines, but for the human brain, this is old news. According to a study by researchers from Denmark and The Netherlands, the brain, just like muscles, works harder during strenuous exercise and is fueled by lactate, rather than glucose.

Not only does this finding help explain why the brain is able to work properly when the body's demands for fuel and oxygen are highest, but it goes a step further to show that the brain actually shifts into a higher gear in terms of activity. This opens doors to entirely new areas of brain research related to understanding lactate's specific neurological effects.

"Now that we know the brain can run on lactate, so to speak, future studies should show us when to use lactate as part of a treatment," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "From an evolutionary perspective, the result of this study is a no-brainer. Imagine what could have or did happen to all of the organisms that lost their wits along with their glucose when running from predators. They were obviously a light snack for the animals able to use lactate."

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